Dr. Christine P. Donahue Lunch Seminar

Friday, November 19th
BUWIC Lunch Seminar: 12:10 to 1:30 pm, Metcalf SCI 512

Christine P. Donahue, Ph.D., Principal Investigator in Aptamer Discovery at Archemix Corp. will join BUWIC for open discussion regarding her research in aptamer chemistry and the career steps she took to achieve her current position. For more information on Dr. Donahue, read her bio below.

Donahue_flier

Christine graduated in 1991 from Fairfield University majoring in Biology. She spent a year working as a laboratory assistant in a clinical lab where she discovered “she liked seeing data more than seeing patients.”  She received her Ph.D. working in Martha Fedor’s lab in the department of Biochemistry and Molecular Biology at the University of Massachusetts Medical School. Her research there was centered on determining the rate of catalysis of the hairpin ribozyme in yeast. Christine next decided to pursue research in a more disease relevant area and joined Ken Kosik’s lab in the Center for Neurologic Disease at Harvard Medical School.  While in his lab she collaborated with Mike Wolfe’s group in evaluating the impact small molecules had on the regulation of mRNA splicing.  As a result of this project, she joined the Wolfe lab and in collaboration with the Laboratory for Drug Discovery in Neurodegeneration, went back to her RNA roots looking for small molecule compounds in a high throughput screen that would bind to an RNA target. In 2007,  she joined Archemix Corp. in Cambridge. She is currently a Principal Investigator leading a group responsible for the discovery and optimization of aptamers.

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