Category: Posts

Functional extinction of birds drives rapid evolutionary changes in seed size

Functional extinction of birds that feed on large seeds in the Brazilian Atlantic forest is associated with reduction in seed size of a palm species.  Seed size is an important trait for many aspects of a plant’s fitness, however, the size of a seed can constrain it’s dispersal capacity by reducing the number of bird […]

Aboriginal Australian genome reveals separate human dispersals into Asia

Sequencing the genome of an Aboriginal Australian indicates that Aborigines diverged ~62,000-75,000 years ago from the gene pool shared by all living non-african humans, and represent a separate migration into Asia from the ancestors of modern Asians, which diverged from european ancestors ~25,000-38,000 years ago.   The authors note that their data is consistent with […]

Potential new therapeutic target for cancer metastasis

Interactions between cancer stem cells and their niche govern metastatic colonization. —   Malanchi, et al., find that infiltrating tumour cells need to induce stromal periostin (POSTN) expression in the secondary target organ to initiate colonization. POSTN is required for cancer stem cell maintenance, and blocking its function prevents metastasis.  POSTN recruits Wnt ligands and thereby […]

Third cnidarian genome published!

Acropora digitifera genome suggests earlier date for anemone-coral divergence of about 500 million years ago, approximately 260 million years earlier than the emergence of reef-building scleractinian corals in the fossil record.