Prime time for GPS2 on The 60 Second Metabolist

Watch Valentina and Carly discussing our most recent findings about the role of GPS2 in the insulin signaling pathway at


Last news feed for 2016: GPS2-mediated inhibition of Ubc13 is essential for proper B cell development

Congratulations to Claudia and all her collaborators! Their work characterizing  GPS2 knock-out in B cells is now in press at JBC:

Job posting: Research Assistant Position available now

The Perissi laboratory in the Biochemistry Department at Boston University  School of Medicine is looking for a motivated research technician to join our young and energetic team.

Both recent college and master graduates are welcome to apply. The position requires a B.S. or B.A. degree of in biology or related biological sciences (a Masters degree is a plus but is not required), and at least 1-2 years of relevant bench experience in a molecular biology lab, including knowledge of mammalian and bacterial cell culture, SDS PAGE, western blotting, PCR, qPCR, DNA and RNA isolation, agarose gel electrophoresis and basic DNA cloning techniques. Animal experience is not required, but the candidate should be comfortable with being trained to handle mice and participate in in vivo experimentation in an approved mouse facilty.

The selected candidate will be involved in an independent research project, but will also be asked to help with ordering supplies and basic laboratory maintenance,  and will assist other laboratory members as needed.

Application can be submitted here:

Please contact Dr. Perissi at for more information.

A novel player in the insulin signaling pathway reported in Molecular Metabolism

Congratulations to Carly and all her co-authors for the exciting discovery of a novel player in the insulin signaling pathway now in press at Molecular Metabolism ( Dissecting the phenotype of GPS2 adipo-specific KO mice has been a long and painful process but the hard work has paid off! Not only a few more tiles have been added to the jigsaw puzzle of GPS2 cellular functions, but this work has revealed an unexpected layer of regulation of the insulin signaling pathway.

New name, new website… same good science

Check out the brand new website of the newly renamed Department of Biochemistry, Cell Biology & Genomics at

Russek Day Student Achievement Award to Carly

Many congratulations to Carly who has been awarded the third prize for this year Russek Day Student Achievement Award!

Join us on Friday, May 6th in Hiebert Lounge to see her poster and participate to the Henry I. Russek Student Achievement Day 2016.  

Welcome Joey!

We are very happy to welcome Joey Orofino, from the PiBS Graduate program, to the lab. Looking forward to many fun discoveries together!

Congratulations to Carly for a well-deserved F31 award!

Kudos to our grad student Carly who has just been awarded a prestigious Kirschstein-NRSA predoctoral fellowship from NIH/NIDDK to study the role of GPS2 in regulating inflammation and lipid metabolism in the adipose tissue. Stay tuned, great discoveries will come….

Welcome to Olivia and Greta!

And finally they are both with us!! A warm welcome to the two youngest members of the lab: Olivia was born on August 16 and Greta on October 3. Two bundles of cuteness, baby fat and lots of hair!! We wish to them and to their moms and dads many days full of joy and many nights of sound sleep! 😉

JBC paper is online!

Congratulations to Jiawen, Dafne and Holly for their paper on the regulation of GPS2 stability now accepted for publication in JBC: