Lab Publications

Mahdaviani K., Benador I.Y., Su S., Gharakhanian R.A., Stiles L., Trudeau K.M., Cardamone M., Enríquez-Zarralanga V., Ritou E,. Aprahamian T., Oliveira M.F., Corkey B.E., Perissi V., Liesa M., Shirihai O.S. Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis.  EMBO Reports, 2017 May 24. [Epub ahead of print]

Lentucci C., Belkina A.*, Cederquist C.T.*, Chan M., Johnson H.E., Prasad S., Lopacinski A., Nikolajczyk B.S., Monti S., Snyder-Cappione J., Tanasa B., Cardamone M.D., Perissi V. Inhibition of Ubc13-mediated ubiquitination by GPS2 regulates multiple stages of B cell development. Journal of Biological Chemistry, 292(7):2754-2772, 2017

Cederquist C.T., Lentucci C., Martinez-Calejman C., Hayashi V., Orofino J., Guertin D., Fried S.K., Lee M.J., Cardamone M.D., Perissi V. Systemic insulin sensitivity is regulated by GPS2 through inhibition of AKT ubiquitination and activation in the adipose tissue. Molecular Metabolism6(1):125-137, 2016.

Huang J*, Cardamone M.D.*, Johnson H.E., Neault M., Chan M., Floyd E.Z., Mallette F.A., Perissi V. Exchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting GPS2 from Proteasomal Degradation. Journal of Biological Chemistry290(31):19044-54, 2015

Cardamone M.D., Tanasa B., Chan M., Cederquist C.T., Andricovich J., Rosenfeld M.G., Perissi V. GPS2/KDM4A Pioneering Activity is required for Promoter-specific PPARgamma binding. Cell Reports 8(1):163-76, 2014

molcel46_1.c1.inddCardamone M.D., Krones A., Tanasa B., Taylor H., Ricci L., Ohgi K.A., Glass C.K., Rosenfeld M.G. & Perissi V. A protective strategy against hyperinflammatory responses requiring the non-transcriptional actions of a component of the NCoR complex, GPS2. Molecular Cell, 46 (1): 91-104, 2012



Perissi V., Jepsen K., Glass C.K. and Rosenfeld M.G. Deconstructing repression: evolving models of corepressors actions. Nature Reviews Genetics, 11(2): 109-23, 2010

Perissi V. and Rosenfeld M.G. Controlling Nuclear Receptors: The Circular Logic of Cofactor Cycles. Nature Reviews Molecular Cell Biology, 6 (7), 542-554, 2005


Other Relevant Publications

Scafoglio C., Smolka M., Zhou H., Perissi V., Rosenfeld MG. The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of Checkpoint Kinase 2 activation. PLOS One 8 (5): e59986, 2013

Perissi V., Scafoglio C., Zhang J., Ohgi K.A., Rose D.W., Glass C.K. & Rosenfeld M.G. Phosphorylation of TBL1 and TBLR1 on Promoters of Regulated Genes Overcomes a Dual Transcriptional Repression Checkpoint Imposed by CtBP and NCoR/SMRT. Molecular Cell, 29 (6), 755-66, 2008

cov200hPerissi V., Aggarwal A., Glass C.K., Rose D.W. & Rosenfeld M.G. A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors, and other regulated transcription factors. Cell, 116(4): 511-26, 2004


Li X., Perissi V., Liu F., Rose D.W., Rosenfeld M.G. Tissue-specific regulation of retinal and pituitary precursor cell proliferation. Science, 16(5584):1180-3, 2002

Wen Y.D., Perissi V., Staszewski L.M., Yang W.M., Krones A., Glass C.K., Rosenfeld M.G., Seto E. The histone deacetylase-3 complex contains nuclear receptor corepressors. PNAS, 97(13), 7202-7207, 2000

Perissi V., Menini N., Cottone E., Capello D., Sacco M., Montaldo F., De Bortoli M. AP-2 transcription factors in the regulation of ERBB2 gene transcription by oestrogen. Oncogene, 19 (2), 280-288, 2000

Perissi V., Staszewski L.M., McInerney E.M., Kurokawa R., Krones A., Rose D.W., Lambert M.H., Milburn M.V., Glass C.K. & Rosenfeld M.G.  Molecular determinants of nuclear receptor-corepressor interaction.  Genes&Development, 13 (24), 3198-3208, 1999

Perissi V., Dasen J.S., Kurokawa R., Wang Z., Korzus E., Rose D.W., Glass C.K., Rosenfeld M.G. Factor specific modulation of CREB-binding protein acetyltransferase activity. PNAS, 96(7), 3652-3657, 1999


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