Scafoglio C., Smolka M., Zhou H., Perissi V., Rosenfeld MG. The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of Checkpoint Kinase 2 activation. PLOS One 8 (5): e59986, 2013

Cardamone M.D., Krones A., Tanasa B., Taylor H., Ricci L., Ohgi K.A., Glass C.K., Rosenfeld M.G. & Perissi V. A protective strategy against hyperinflammatory responses requiring the non-transcriptional actions of a component of the NCoR complex, GPS2. Molecular Cell, 46 (1): 91-104, 2012.


Perissi V., Jepsen K., Glass C.K. and Rosenfeld M.G. Deconstructing repression: evolving models of corepressors actions. Nature Reviews Genetics, 11(2): 109-23, 2010.

Huang W., Ghisletti S., Perissi V., Rosenfeld M.G. & Glass C.K. Gene-specific transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint. Molecular Cell, 35(1):48-57, 2009.

Perissi V., Scafoglio C., Zhang J., Ohgi K.A., Rose D.W., Glass C.K. & Rosenfeld M.G. Phosphorylation of TBL1 and TBLR1 on Promoters of Regulated Genes Overcomes a Dual Transcriptional Repression Checkpoint Imposed by CtBP and NCoR/SMRT. Molecular Cell, 29 (6), 755-66, 2008.

Jepsen K., Perissi V., Lunyak V., Glass C.K. and Rosenfeld M.G. Mechanisms of regulated gene transcription. Inborn Errors of Development, II Edition, Oxford Univ Press, 2008.

Pascual G., Sullivan A.L., Ogawa S., Gamliel A., Perissi V., Rosenfeld M.G., Glass C.K. Anti-inflammatory and antidiabetic roles of PPARgamma. Novartis Found Symp. 286: 183-203, 2007.

Ju B-G., Lunyak V.V., Perissi V., Garcia-Bassets I., Rose D.W., Glass C.K. & Rosenfeld M.G. A Topoisomerase IIß-Mediated dsDNA Break Required for Regulated Transcription. Science, 312 (5781), 1798 – 1802, 2006.

Perissi V. and Rosenfeld M.G. Controlling Nuclear Receptors: The Circular Logic of Cofactor Cycles. Nature Reviews Molecular Cell Biology, 6 (7), 542-554, 2005

Pascual P., Fong A.L., Ogawa S., Gamliel A., Li A.C., Perissi V., Rose D.W., Willson T., Rosenfeld M.G. & Glass C.K. PPARg-dependent repression of inflammatory response genes mediated by an evolutionarily conserved sumoylation-dependent pathway. Nature, 437 (7059), 759-63, 2005.

Ogawa S., Lozach J., Jepsen K., Sawka-Verhelle D., Perissi V., Sasik R., Rose D.W., Johnson R.S., Rosenfeld M.G. and Glass C.K. An NCoR transcriptional checkpoint controlling AP-1-dependent gene networks required for macrophage activation. PNAS, 101(40), 14461-14466, 2004.

Perissi V., Aggarwal A., Glass C.K., Rose D.W. & Rosenfeld M.G. A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors, and other regulated transcription factors. Cell, 116(4): 511-26, 2004.



Li X., Perissi V., Liu F., Rose D.W. & Rosenfeld M.G.  Tissue-specific regulation of retinal and pituitary precursor cell proliferation.  Science, 16(5584):1180-3, 2002.

Wen Y.D., Perissi V., Staszewski L.M., Yang W.M., Krones A., Glass C.K., Rosenfeld M.G. & Seto E.  The histone deacetylase-3 complex contains nuclear receptor corepressors.  PNAS, 97(13), 7202-7207, 2000.

Perissi V., Menini N., Cottone E., Capello D., Sacco M., Montaldo F. & De Bortoli M.  AP-2 transcription factors in the regulation of ERBB2 gene transcription by oestrogen. Oncogene, 19 (2), 280-288, 2000.

Perissi V., Staszewski L.M., McInerney E.M., Kurokawa R., Krones A., Rose D.W., Lambert M.H., Milburn M.V., Glass C.K. & Rosenfeld M.G.  Molecular determinants of nuclear receptor-corepressor interaction.  Genes&Development, 13 (24), 3198-3208, 1999.

Perissi V., Dasen J.S., Kurokawa R., Wang Z., Korzus E., Rose D.W., Glass C.K. & Rosenfeld M.G. Factor specific modulation of CREB-binding protein acetyltransferase activityPNAS, 96(7), 3652-3657, 1999.