{"id":1161,"date":"2013-02-26T10:59:15","date_gmt":"2013-02-26T15:59:15","guid":{"rendered":"http:\/\/blogs.bu.edu\/ellisrp\/?p=1161"},"modified":"2013-02-26T10:59:15","modified_gmt":"2013-02-26T15:59:15","slug":"nejm-study-says-eat-olive-oil-and-nuts","status":"publish","type":"post","link":"https:\/\/blogs.bu.edu\/ellisrp\/2013\/02\/nejm-study-says-eat-olive-oil-and-nuts\/","title":{"rendered":"NEJM Study Says Eat Olive Oil and Nuts"},"content":{"rendered":"<p>There has been a lot of news recently about a NEJM randomized trial\u00a0 Spanish study of diets that shows\u00a0 statistically significant benefits of two Mediterranean diets, one providing free olive oil, the other providing free nuts (mostly walnuts), along with other diet recommendations.Scientists randomly assigned 7,447 men and women in Spain over age 55 who were overweight,  were smokers, or had diabetes or other risk factors for heart disease to  follow the Mediterranean diet or a low-fat diet as the control group. Here is the key paragraph from the NY Times.<\/p>\n<p>&#8220;One group assigned to a Mediterranean diet was given extra-virgin olive  oil each week and was instructed to use at least 4 four tablespoons a  day. The other group got a combination of walnuts, almonds and hazelnuts  and was instructed to eat about an ounce of the mix each day. An ounce  of walnuts, for example, is about a quarter cup \u2014 a generous handful.&#8221;<\/p>\n<p>The articles in the Times and Post have emphasized that it was the Mediterranean diet, but the following important blog from Dr. Aaron Carroll, highlights that it very likely that the effects were solely due to increased olive oil and nuts, since the three groups do not differ meaningfully in their consumption of other foods (red meat, fish, vegetables, fruit, grains, red wine, etc.).\u00a0 Hence instead of saying &#8220;Go Mediterranean&#8221;, it should have said &#8220;Eat Olive Oil and Nuts&#8221; to reduce heart and stroke risks.<\/p>\n<p>See table linked in this blog.<\/p>\n<h2><a href=\"http:\/\/theincidentaleconomist.com\/wordpress\/now-were-all-going-mediterranean\/\" title=\"Now we\u2019re all going Mediterranean?\">Now we\u2019re all going Mediterranean?<\/a><\/h2>\n<blockquote class=\"wp-embedded-content\" data-secret=\"FxfKJoGxY0\"><p><a href=\"https:\/\/theincidentaleconomist.com\/wordpress\/now-were-all-going-mediterranean\/\">Now we&#8217;re all going Mediterranean?<\/a><\/p><\/blockquote>\n<p><iframe class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" src=\"https:\/\/theincidentaleconomist.com\/wordpress\/now-were-all-going-mediterranean\/embed\/#?secret=FxfKJoGxY0\" data-secret=\"FxfKJoGxY0\" width=\"600\" height=\"338\" title=\"&#8220;Now we&#8217;re all going Mediterranean?&#8221; &#8212; The Incidental Economist\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p>More work should be done in this area.<\/p>\n<p>Here is the full cite and abstract from the NEJM.<\/p>\n<h1>Primary Prevention of Cardiovascular Disease with a Mediterranean Diet<\/h1>\n<p>Ram\u00f3n  Estruch, M.D., Ph.D., Emilio Ros, M.D., Ph.D., Jordi Salas-Salvad\u00f3,  M.D., Ph.D., Maria-Isabel Covas,  D.Pharm., Ph.D., Dolores Corella,  D.Pharm., Ph.D., Fernando Ar\u00f3s, M.D., Ph.D., Enrique G\u00f3mez-Gracia, M.D.,  Ph.D., Valentina Ruiz-Guti\u00e9rrez, Ph.D., Miquel Fiol, M.D., Ph.D., Jos\u00e9  Lapetra, M.D., Ph.D., Rosa Maria Lamuela-Raventos, D.Pharm., Ph.D.,  Llu\u00eds Serra-Majem, M.D., Ph.D., Xavier Pint\u00f3, M.D., Ph.D., Josep Basora,  M.D., Ph.D., Miguel Angel Mu\u00f1oz, M.D., Ph.D., Jos\u00e9 V. Sorl\u00ed, M.D.,  Ph.D., Jos\u00e9 Alfredo Mart\u00ednez, D.Pharm, M.D., Ph.D., and Miguel Angel  Mart\u00ednez-Gonz\u00e1lez, M.D., Ph.D. for the PREDIMED Study Investigators<\/p>\n<p>February 25, 2013DOI:  10.1056\/NEJMoa1200303<\/p>\n<p>http:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1200303?query=featured_home#t=article<\/p>\n<p>Abstract: The traditional Mediterranean diet is characterized by a high intake of  olive oil, fruit, nuts, vegetables, and cereals; a moderate intake of  fish and poultry; a low intake of dairy products, red meat, processed  meats, and sweets; and wine in moderation, consumed with meals. In observational cohort studies and a secondary prevention trial (the Lyon Diet Heart Study), increasing adherence to the Mediterranean diet has been consistently beneficial with respect to cardiovascular risk.  A systematic review ranked the Mediterranean diet as the most likely  dietary model to provide protection against coronary heart disease. Small clinical trials have uncovered plausible biologic mechanisms to explain the salutary effects of this food pattern.  We designed a randomized trial to test the efficacy of two  Mediterranean diets (one supplemented with extra-virgin olive oil and  another with nuts), as compared with a control diet (advice on a low-fat  diet), on primary cardiovascular prevention.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>There has been a lot of news recently about a NEJM randomized trial\u00a0 Spanish study of diets that shows\u00a0 statistically significant benefits of two Mediterranean diets, one providing free olive oil, the other providing free nuts (mostly walnuts), along with other diet recommendations.Scientists randomly assigned 7,447 men and women in Spain over age 55 who &hellip; <a href=\"https:\/\/blogs.bu.edu\/ellisrp\/2013\/02\/nejm-study-says-eat-olive-oil-and-nuts\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">NEJM Study Says Eat Olive Oil and Nuts<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2755,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[7238],"tags":[252],"_links":{"self":[{"href":"https:\/\/blogs.bu.edu\/ellisrp\/wp-json\/wp\/v2\/posts\/1161"}],"collection":[{"href":"https:\/\/blogs.bu.edu\/ellisrp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.bu.edu\/ellisrp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.bu.edu\/ellisrp\/wp-json\/wp\/v2\/users\/2755"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.bu.edu\/ellisrp\/wp-json\/wp\/v2\/comments?post=1161"}],"version-history":[{"count":2,"href":"https:\/\/blogs.bu.edu\/ellisrp\/wp-json\/wp\/v2\/posts\/1161\/revisions"}],"predecessor-version":[{"id":1163,"href":"https:\/\/blogs.bu.edu\/ellisrp\/wp-json\/wp\/v2\/posts\/1161\/revisions\/1163"}],"wp:attachment":[{"href":"https:\/\/blogs.bu.edu\/ellisrp\/wp-json\/wp\/v2\/media?parent=1161"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.bu.edu\/ellisrp\/wp-json\/wp\/v2\/categories?post=1161"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.bu.edu\/ellisrp\/wp-json\/wp\/v2\/tags?post=1161"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}